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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PCNXL2 All Species: 9.09
Human Site: S408 Identified Species: 20
UniProt: A6NKB5 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NKB5 NP_055616.3 2137 237277 S408 T E K T S V K S D A E P T N P
Chimpanzee Pan troglodytes XP_514278 2131 236804 S408 T E K T S V K S D A E P T N P
Rhesus Macaque Macaca mulatta XP_001103740 1934 214216 P286 H S S S S R E P W E S A S R L
Dog Lupus familis XP_546085 1964 218241 S317 G H A T K D G S P S P G D C C
Cat Felis silvestris
Mouse Mus musculus Q5DU28 2122 234109 T393 S S L H L R V T S S D R T S V
Rat Rattus norvegicus XP_001055579 2154 238039 P401 S D R T G V R P N A E N A G P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_423893 2312 255194 F528 G K K R A S S F D S S R H R E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres Q98UF7 1703 191329 S56 L Y M A L Q P S M V I V G I Y
Fruit Fly Dros. melanogaster P18490 3433 367590 H727 E K T A H E E H G D D C L G I
Honey Bee Apis mellifera XP_624687 2092 236172 K410 E S K A D K S K N I D D P L N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001195494 2799 311472 T534 D K Q R I R H T G S I S T A D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 86.1 79.4 N.A. 80.4 78.5 N.A. N.A. 39.8 N.A. N.A. 41.7 27.4 33.8 N.A. 32.8
Protein Similarity: 100 99.3 87.8 84.5 N.A. 88 86.1 N.A. N.A. 54.8 N.A. N.A. 55.4 40.7 51.4 N.A. 46.7
P-Site Identity: 100 100 6.6 13.3 N.A. 6.6 33.3 N.A. N.A. 13.3 N.A. N.A. 6.6 0 6.6 N.A. 6.6
P-Site Similarity: 100 100 26.6 20 N.A. 40 66.6 N.A. N.A. 33.3 N.A. N.A. 6.6 20 20 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 28 10 0 0 0 0 28 0 10 10 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 10 0 10 10 % C
% Asp: 10 10 0 0 10 10 0 0 28 10 28 10 10 0 10 % D
% Glu: 19 19 0 0 0 10 19 0 0 10 28 0 0 0 10 % E
% Phe: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % F
% Gly: 19 0 0 0 10 0 10 0 19 0 0 10 10 19 0 % G
% His: 10 10 0 10 10 0 10 10 0 0 0 0 10 0 0 % H
% Ile: 0 0 0 0 10 0 0 0 0 10 19 0 0 10 10 % I
% Lys: 0 28 37 0 10 10 19 10 0 0 0 0 0 0 0 % K
% Leu: 10 0 10 0 19 0 0 0 0 0 0 0 10 10 10 % L
% Met: 0 0 10 0 0 0 0 0 10 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 19 0 0 10 0 19 10 % N
% Pro: 0 0 0 0 0 0 10 19 10 0 10 19 10 0 28 % P
% Gln: 0 0 10 0 0 10 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 10 19 0 28 10 0 0 0 0 19 0 19 0 % R
% Ser: 19 28 10 10 28 10 19 37 10 37 19 10 10 10 0 % S
% Thr: 19 0 10 37 0 0 0 19 0 0 0 0 37 0 0 % T
% Val: 0 0 0 0 0 28 10 0 0 10 0 10 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _